CytoQuest™ Dx

Automated bio-robotics for positive enrichment and retrieval of CTCs, CSCs, and EVTs.

Three major subtypes of circulating rare cells in clinical applications are circulating tumor cells (CTCs), circulating cancer stem cells (CSCs), and circulating extravillous trophoblasts (EVTs). Abnova's CytoQuest™ Dx is a revolutionary bio-robotic automation for isolation of CTCs. CytoQuest™ Dx leverages the positive enrichment, microfluidic technology of CytoQuest™ CR for CTC capture and automates all the physical operations involved in antibody immobilization, sample loading, CTC immuno-labeling and staining. It provides unprecedented precision, accuracy, and reproducibility required for clinical adoption.

CytoQuest™ Dx combines microfluidics, XYZ liquid handler, robotics, sensors and smart software to perform complex biological tasks of CTC isolation. Starting from prepared blood sample in collection tube, the XYZ and 6-axial robotic arm simulate pipetting, aspirating, transferring, washing, labeling and staining of CTCs on the chip, sample chamber, and microfluidic modules. The versatile robotic arm is guided by a multitude of real-time optical, electrical, and mechanical sensors, and intelligent algorithm for high throughput and multi-task functions. The entire workflow is operated under a self-contained, HEPA filtered environment to minimize cross contamination.

CytoQuest™ Dx meets the rigorous requirements of high volume and precision sample processing by bridging a seamless transition from CytoQuest™ CR clinical research platform to a robust in vitro diagnostic workstation. CytoQuest™ Dx is supported by same repertoire of circulating epithelial and tumor cell kits, FISH probes, and peripheral bioreagents as for CytoQuest™ CR. CytoQuest™ Dx is a powerful, positive selection platform in the growing field of CTCs and derived clinical applications.

 

CRC subtypes


  • Circulating Tumor Cells (CTCs)
  • Cancer Stem Cells (CSCs)
  • Extravillous Trophoblasts (EVTs)


CytoQuest™ Dx Advantages


  • Precision, Accuracy & Reproducibility
  • High Throughput & Multi-Tasking
  • Minimize Cross Contaminations
  • Positive Selection Cell Isolation


CytoQuest™ Dx Integration


  • Total Solution Workstation
  • XYZ Axis and 6 Axial Robotic Arm
  • In-Process Controls & Sensors
  • Intelligent Software Algorithm
  • Self-Contained Modules
  • RFID Consumable Tracking
  • Clean Environment & HEPA Filter

CytoQuest™ Dx




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